Peptic ulcer and milk?

13 11 2010

So I had an interesting debate with my colleague on what the actions of milk would do to a patient with peptic ulcer. Since we looked on UpToDate and found that this was an article referenced, but was written in 1976, I would like to find more recent articles to prove its disbenefits.

Even WebMD had an article that suggests against it. Milk has proteins & causes more peptic acid secretion from the stomach so it is contraindicated in patients with GERD or peptic ulcer. And all along when I mentioned it during ICM interview, no one corrected me.  It’s important to note that now …

Medline ® Abstract for Reference 75

of ‘Peptic ulcer disease: Genetic, environmental, and psychological risk factors and pathogenesis’

The effect of various forms of milk on gastric-acid secretion. Studies in patients with duodenal ulcer and normal subjects.
Ippoliti AF; Maxwell V; Isenberg JI
Ann Intern Med 1976 Mar;84(3):286-9.
“Milk is commonly recommended as therapy for patients with peptic ulcer. The purpose of this study was to examine the effect of various forms of milk and 0.15 M NaCl (control) on gastric-acid secretion in five patients with duodenal ulcer during a period of remission and in five normal subjects. A significant (P less than 0.05) increase in acid secretion in both groups was produced by 240 ml of whole, low-fat, and nonfat milk. The acid secretory responses to milk were equivalent to approximately 20% to 35% of maximal betazole – or pentagastrin-stimulated acid output. Gastric-acid secretion produced a significant (P less than 0.05) increase in acid secretion in the patients with duodenal ulcer but not in the normal subjects. Because milk contains both protein and calcium, and each are stimulants of gastric-acid secretion, there is reason to question its frequent ingestion by patients with peptic ulcer.”